A fictional, modern-day scenario is juxtaposed with the deadly 1885 Montreal smallpox epidemic.
Patient Zero is a flight attendant, stricken with what she thinks is chicken pox. She lands in Montreal and goes to a hotel room to recover. A few weeks later she is back on the job - unaware of her role in an impending public health catastrophe. OUTBREAK: ANATOMY OF A PLAGUE juxtaposes this fictional, modern-day scenario with the 1885 Montreal smallpox epidemic during which 20,000 people were infected and 3,000 died. Based on Michael Bliss' gripping book, it reveals the alarming reality that, more than a century later, our modern world may not be ready for the next deadly outbreak.